Defining heterochromatin in C. elegans through genome-wide analysis of the heterochromatin protein 1 homolog HPL-2

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Figure 3.
Figure 3.

HPL-2 binding and CeCENP-A incorporation generally do not co-occur. (AC) Comparisons of HPL-2 and CeCENP-A ChIP-chip signal in chromosome arms (left) versus centers (right). (A) Mean Z-scores of HPL-2 and CeCENP-A over 2-kbp regions. (B) Mean Z-scores with 95% confidence intervals of HPL-2 (blue) and CeCENP-A (red) over regions surrounding and across CeCENP-A domains. CeCENP-A domains were scaled to their average size (10 kbp). (C) Mean Z-scores of HPL-2 (blue) and CeCENP-A (red) distributed over representative 1.2-Mbp regions.

This Article

  1. Genome Res. 25: 76-88

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