Figure 1.
Prediction performance of BLUP and MultiBLUP on simulated quantitative traits. The two plots correspond to unrelated humans (left) and related mice (right). They show across 50 repetitions the correlation between predicted and observed phenotypes in the test set for BLUP (white boxes) and MultiBLUP (shaded boxes). The x-axis indexes the simulation scenarios, with increasing heterogeneity of effect sizes across the five regions. Here, MultiBLUP uses five GSMs, one for each region. Within each plot, the true (simulated) heritability is 0.5 (left half) or 0.8 (right half).
