Selective enrichment of damaged DNA molecules for ancient genome sequencing

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2.
Figure 2.

C to T substitution frequencies as functions of the alignment position in sequences obtained from a Neanderthal sample (Vi33.17) after U selection. Libraries were prepared with and without excision of internal uracils by UDG prior to U selection. Plots are shown for both library fractions (uracil-enriched supernatant and uracil-depleted bead fraction).

This Article

  1. Published in Advance July 31, 2014, doi: 10.1101/gr.174201.114 Genome Res. 24: 1543-1549

Preprint Server



Current Issue

  1. February 2026, 36 (2)
  1. Current Issue
  1. Alert me to new issues of Genome Research