Figure 7.
Shared enhancer function among three ASCs derived from primate-specific L1PA repeats. (A) Three ASC elements drove consistent lacZ expression in the developing eye at E14.5. Three representative embryos are shown for each construct; the full sets can be found in Supplemental Figures S10–S12. (B) De novo motif discovery in the tested TE-ASCs uncovered binding motifs similar to the known motifs of TCF3 and SIX6. In situ hybridization, sagittal sections: Tcf3 and Six6 show strongest expression in the eye at E14.5.
