Error-prone polymerase activity causes multinucleotide mutations in humans

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Figure 7.
Figure 7.

Two estimates of MNM prevalence. Here, the black lines plot ct(L), our SFS-based estimate of the fraction of perfect LD mutations caused by MNM. For comparison, gray lines plot the estimate mt(L) that is based on the excess of same-lineage derived alleles over different-lineage derived alleles in subsampled haplotype pairs.

This Article

  1. Published in Advance July 30, 2014, doi: 10.1101/gr.170696.113 Genome Res. 24: 1445-1454

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