Error-prone polymerase activity causes multinucleotide mutations in humans

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Figure 3.
Figure 3.

The fraction of SNPs in perfect LD caused by MNM. The dash-dotted curve plots our estimate of the fraction of transversions in perfect LD at distance L that were caused by simultaneous mutation. It is uniformly higher than our corresponding estimates for mixed pairs and transitions, plotted with solid and dashed lines.

This Article

  1. Published in Advance July 30, 2014, doi: 10.1101/gr.170696.113 Genome Res. 24: 1445-1454

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