Reconfiguration of nucleosome-depleted regions at distal regulatory elements accompanies DNA methylation of enhancers and insulators in cancer

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Figure 6.
Figure 6.

CTCF, RAD21, and REST are associated with patterns of nucleosome organization. (A–C) Nucleosome occupancy (teal lines) and endogenous methylation (CpG; black lines) were mapped ±1000 bp from the center (“0”) of each transcription factor binding site (CTCF, REST, and RAD21) and were determined to be “strongly phased” in MCF7 cells.

This Article

  1. Genome Res. 24: 1421-1432

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