Figure 3.
Distribution of 5mC and 5hmC around CTCF sites in ESCs, NPCs, and MEFs. (A) 5mC density calculated around constitutive (“ESC and MEF”), variable (“ESC not MEF”), and weak (“MEF not ESC”) CTCF sites in ESCs from the published CTCF ChIP-seq data (Shen et al. 2012). (B) Same as panel A but for the hydroxymethylation modification at CpGs. (C) 5mC density in ESCs at “ESC and NPC,” “ESC not NPC,” and “NPC not ESC” CTCF sites calculated with CTCF ChIP-seq data in ESCs (Shen et al. 2012) and NPCs (Phillips-Cremins et al. 2013). (D) Same as panel C but for 5mC density in NPCs.
