A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection

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Figure 4.
Figure 4.

Functional validation of miRNA–mRNA relationships using miR-29a gain- and loss-of-function experiments. (A,B) Boxplots showing absolute fold changes in genome-wide mRNA levels of cells transfected with either an miR-29a mimic (A) or an miR-29 inhibitor (B) and subsequently infected with MTB. (C,D) Cumulative distributions of changes in genome-wide mRNA levels after transfection with the mimic (C) or the inhibitor (D) in MTB-infected cells.

This Article

  1. Published in Advance January 30, 2014, doi: 10.1101/gr.161471.113 Genome Res. 24: 850-859

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