A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection

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Figure 2.
Figure 2.

MiR-eQTLs upon infection. (A) Boxplots showing the detected response miR-eQTLs in cis for miR-326 and miR-1260, in non-infected and infected samples. (B) Regional association plot for miR-582-5p and genotyped SNPs in the region of the gene PDE4D showing the location of a cluster of significantly associated SNPs ∼500 kb upstream of the miRNA in infected samples. An additional region, in between the detected eQTL and the miRNA, also showed a strong tendency of association; however, this did not reach genome-wide significance. All annotations are based on UCSC hg19.

This Article

  1. Genome Res. 24: 850-859

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