Age-related epigenetic drift in the pathogenesis of MDS and AML

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Figure 5.
Figure 5.

Methylation analysis of repetitive elements in mouse. (A) Methylation profiles of LINE-1, SINE B1, and major satellite DNA by pyrosequencing analysis. (B) Association of the methylation percentages between LINE-1 (y-axis), SINE B1 (x-axis), and major satellite DNA (x-axis) in all samples. Sample codes are on the right. The Spearman test was used to determine correlations, with significance set at P < 0.05. R represents a measure of the linear relationship between two variables, and varies from −1 to +1.

This Article

  1. Published in Advance January 10, 2014, doi: 10.1101/gr.157529.113 Genome Res. 24: 580-591

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