Genome-wide views of the regions with editing sites piled with the mapped reads of ICE-seq. (A) Q/R and Q/Q sites in exon 11 of GRIA2 mRNA. (B) I/M site in GABRA3 mRNA. (C) Editing cluster in 3′ UTR of BPNT1 mRNA. Top panel shows histograms of the mapped reads under CE− conditions at genomic positions. Genome number, positions, and scale of length are indicated. Middle panel shows close-up views of the regions with editing sites piled with the mapped reads in conditions of CE− (blue), CE+ (orange), and CE++ (pink). Bottom panel shows the decreased read ratio upon cyanoethylation (CE++) (gray downward peaks) and editing sites with the decreased ratio of G-base counts upon cyanoethylation (CE++) (red bars).
