
Large-scale changes following chromosomal rearrangements. (A) Ideogram of human chromosome 2 showing changes in recombination rate in humans and chimpanzees. Each impulse represents ancestral rate minus human rate (red) or ancestral rate minus chimpanzee rate (blue) in 2-Mb bins. The dotted vertical line marks the point of fusion of the ancestral chromosomes 2a and 2b. (B) Ideogram of human chromosome 18. The dashed line encloses the region of inversion in the human lineage.











