A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes

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Figure 3.
Figure 3.

Distribution of downstream (A) and upstream (B) nucleotides for editing sites detected in the HBM data sets. Edited sites are split into three groups according to their editing level: low level ≤10%, high level ≥40%, and medium level >10% and <40%. A clear signature of the ADAR sequence preference is observed (low G upstream of the site, and some enrichment downstream from the site). The preference is stronger at sites with high editing levels.

This Article

  1. Published in Advance December 17, 2013, doi: 10.1101/gr.164749.113 Genome Res. 24: 365-376

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