Nucleosome organization predicts H3K4me3 and transcription. Genes are grouped evenly into five bins based on promoter nucleosome array value at the 256-cell stage. G1 represents the lowest nucleosome array value, G5 the highest. The sum of the fractions of five groups is 1. (A) The fraction of genes marked by H3K4me3 at promoters at the oblong (black) and dome (gray) stage for each group. (B) The fraction of genes transcribed at the dome stage in each group. Transcription status is inferred from H3K36me3 ChIP-seq enrichment in exons and RNA Pol II ChIP-seq enrichment in gene bodies. Likelihood ratio test of linear correlation is used to calculate P-value.
