Large-scale hypomethylated blocks associated with Epstein-Barr virus–induced B-cell immortalization

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Figure 1.
Figure 1.

DNA methylation and gene expression changes following EBV transformation and CD40L/IL4 activation. The number of differentially methylated regions (DMRs), differentially expressed (DE) genes, and bases covered by hypomethylated blocks is listed for each condition. Numbers after the slash are at a family-wise error rate of <5% using permutation testing. Differences specific to the process of transformation (dashed line) were identified by comparing EBV immortalized B-cells to CD40L/IL4 activated B-cells.

This Article

  1. Genome Res. 24: 177-184

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