Heritable variation of mRNA decay rates in yeast

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 3.
Figure 3.

mRNA decay rates in yeast are often coupled to opposite changes in transcription initiation. (Left) Venn diagram showing the overlap of genes with significant allelic differences in steady-state gene expression (ASE) and decay (ASD). (Right) Scatter plot showing estimates of differences in decay rates between BY and RM (x-axis) versus the proportion of transcripts from the BY allele (pBY) inferred from the 0-min time point for genes with both ASE and ASD. The shaded gray rectangles represent quadrants where magnitudes of ASD and ASE are discordant, suggesting compensatory evolution.

This Article

  1. Genome Res. 24: 2000-2010

Preprint Server