Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C

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Figure 7.
Figure 7.

ChIP qPCR analysis of FOXA1 binding to rs4442975 region. (A) FOXA1 ChIP-qPCR for MYC (positive control), rs4442975 (test region), and a control region (Chr2: 217,922,940–217,923,055 bp) mapping 2.1 kb telomeric to rs4442975 that showed no evidence of FOXA1 binding in data from Hurtado and colleagues. Mean ±SD for three technical replicates. (B) Sanger sequencing of the rs4442975 region in FOXA1 immunoprecipitated chromatin (top) and input genomic DNA (bottom).

This Article

  1. Genome Res. 24: 1854-1868

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