Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition

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Figure 5.
Figure 5.

Indel rates in homopolymers in the absence of MMR. (A) A comparison of nucleosome density (red; relative to the +1 peak) and pol2-M644G mmr- AT deletion rates (blue) as a function of distance from translation start sites. (B) Homopolymer densities (relative to maximum density) for various homopolymer lengths as a function of distance from translation start sites.

This Article

  1. Published in Advance September 12, 2014, doi: 10.1101/gr.178335.114 Genome Res. 24: 1751-1764

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