Phase interference model applied to convergent gene pairs. (A) A nucleosomal array formed on the DNA between convergent TSSs. If a regular array of nucleosomes has a repeat length of 165 bp and the dyads of the +1 nucleosomes at both ends of the array are located at a distance ∆ downstream from the TSS, then the inter-TSS distance is 165n + 2∆, where n is an integer equal to the number of nucleosomal repeats (Δ = 45 or 28 bp for wild-type and Rsc8-depleted cells, respectively; see Fig. 2B). (B) Constructive interference: nucleosomal arrays phased relative to both TSSs are in phase. Destructive interference: the nucleosomal array phased relative to the reference TSS is out of phase with the array phased relative to the other TSS. The relative phase of the two arrays depends on the inter-TSS distance.
