C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency

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Figure 5.
Figure 5.

Patterns of dinucleotide substitutions observed. (A) Numbers of dinucleotide substitutions in animals propagated for 20 generations and those exposed to the different carcinogens. (B) Dinucleotide substitutions in cisplatin-exposed animals. The sequences of the dinucleotides that are mutated are on the x-axis and what they are mutated to is denoted by the color of the bar.

This Article

  1. Published in Advance July 16, 2014, doi: 10.1101/gr.175547.114 Genome Res. 24: 1624-1636

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