The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity

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Figure 1.
Figure 1.

DEK associates with PML NBs. (A) Immunofluorescence localization of DEK and PML in nuclei of human MSCs. Graph shows fluorescence intensity of PML and DEK along the line drawn on the merged image. (B) Immunofluorescence localization of DEK in cells expressing EGFP-PML. Arrows point to sites of DEK and PML colocalization. Bars, 10 µm. (C) Western blot analysis of PML and DEK immune precipitates (IP) from MSC lysates. Control immunoprecipitations were done using an anti-FLAG antibody.

This Article

  1. Published in Advance July 21, 2014, doi: 10.1101/gr.173831.114 Genome Res. 24: 1584-1594

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