The roles of cis- and trans-regulation in the evolution of regulatory incompatibilities and sexually dimorphic gene expression

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Figure 4.
Figure 4.

Allele-specific expression among genes assayed by pyrosequencing within the introgressed region. (A) Log2 ratios of allelic expression (D. mauritiana/D. simulans) in males and females. Trend lines were obtained by loess smoothing using a span of 0.2. The candidate region containing local sexually dimorphic cis-regulatory effects is indicated in gray. (B) Differences in allelic expression between males and females as a function of location. The trend line was obtained by loess smoothing using a span of 0.2. The candidate region with sexually dimorphic cis-regulatory effects is apparent as a net excess of D. mauritiana allelic expression in males, due to strong overexpression of the D. simulans allele in females.

This Article

  1. Genome Res. 24: 84-95

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