Natural variation in the histone demethylase, KDM4C, influences expression levels of specific genes including those that affect cell growth

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Figure 1.
Figure 1.

Chromosome 9p24 that includes KDM4C is a gene expression regulatory region. (A) Linkage plots for four gene expression phenotypes that show significant linkage to chromosome 9p24. (B) Results from QTDT and population association with SNPs in expressed genes under the linkage peaks for expression levels of four genes. Expressed genes are depicted in green; genes that are in the region but not expressed in B cells are shown in black. KDM4C is shown in red, and the KDM4C gene region is boxed.

This Article

  1. Genome Res. 24: 52-63

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