Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods

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Figure 3.
Figure 3.

CRF versus HMM. (A) In an HMM, the labels generate the observations, while in a CRF, co-occurrences of the label and observations are associated. (B) HMMs model the joint probability and must consequently model the dependencies in the observations, while CRFs only model the dependencies of the label on the data.

This Article

  1. Published in Advance June 26, 2013, doi: 10.1101/gr.152231.112 Genome Res. 23: 1541-1553

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