Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods

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Figure 1.
Figure 1.

Relationship between MeDIP-seq and MRE-seq and MethylC-seq. (A) A kernelized density plot of per CpG MeDIP-seq normalized read count values as a function of MethylC-seq methylation levels shows a complex, approximately proportional relationship. (B) MRE-seq normalized read counts as a function of MethylC-seq methylation levels shows a complex, approximately inversely proportional relationship.

This Article

  1. Genome Res. 23: 1541-1553

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