Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm

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Figure 4.
Figure 4.

Tissue-specific DMRs are enriched for regulatory histone modifications. (A) H3K4me1 and H3K4me3 profiles at tissue-specific DMRs in H1 ESCs, CD4 memory T cells, breast myoepithelial cells, and fetal brain tissue. (B) ChromHMM regulatory function annotation of tissue-specific DMRs. (C) Expression of genes near tissue-specific DMRs in samples representing different tissues.

This Article

  1. Published in Advance June 26, 2013, doi: 10.1101/gr.156539.113 Genome Res. 23: 1522-1540

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