Figure 3.
(A,B) A/T and C/G dinucleotide incidence rates around representative outron-TSSs (A) and exon-TSSs (B) of expression levels ≥10 and ≥100 (see the distribution for Gaussian TSSs in Supplemental Fig. S2E,F). AT richness immediately upstream of outron-TSSs is due to the requirement for SL1 splicing motif “TTTTCAG.” In both types of TSSs, a significant valley in the A/T rate and a significant peak in the C/G rate were observed ∼100 bp upstream of TSSs. (C) A/T and C/G dinucleotide incidence rates around SL1 sites and 5′ ends of exons. In all graphs, a running average over a 20-bp window is shown for smoothing lines.
