Mapping functional transcription factor networks from gene expression data

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Figure 5.
Figure 5.

(A) The top seven NetProphet-predicted targets of Eds1 are all in the pathway for conversion of cytosolic citrate to lysine. (B) Log2-fold change of EDS1 and five lysine biosynthesis genes relative to wild-type cells in an eds1 deletion mutant (two replicate cultures) and the same deletion mutant complemented by overexpression of Eds1 under the control of the tetO2 promoter (cultures of two independent transformants).

This Article

  1. Published in Advance May 1, 2013, doi: 10.1101/gr.150904.112 Genome Res. 23: 1319-1328

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