Clusters of genes are up-regulated in response to pathogen infection in N2 and rde-1, but not in JU1580. (A) The distance between any greater than twofold up-regulated gene and its nearest neighbor that is also greater than twofold up-regulated in N2 and rde-1 as a histogram. (B) The histogram of distances for genes that are greater than twofold up-regulated in JU1580 as well as N2 and/or rde-1. (C) A diagram of the sdz-6 locus as an example of a cluster up-regulated upon viral infection. (Boxes) Gene bodies; (gray box) the region deleted in the Hawaiian strain CB4856. Information was taken from WormBase (http://www.wormbase.org). (D) The expression changes in the sdz-6 cluster from the array data in N2, rde-1, and JU1580. Bars represent the mean of all biological replicates. (E) PCR amplification of genomic DNA from JU1580 or N2 for three regions within the cluster or the nearby gene srh-208.
