An integrative variant analysis pipeline for accurate genotype/haplotype inference in population NGS data

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Figure 1.
Figure 1.

Overview of the SNPTools Pipeline. The SNPTools pipeline utilizes binary sequence map (BAM) files and then processes them through four modular steps: calculation of effective base depth (EBD), SNP site discovery, BAM-specific binomial mixture modeling (BBMM) to calculate genotype likelihoods, and genotype and haplotype imputation.

This Article

  1. Published in Advance January 7, 2013, doi: 10.1101/gr.146084.112 Genome Res. 23: 833-842

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