Figure 2.
Enrichment for SNPs but not indels in recombination hotspots. Density of SNPs (left) and indels (right) in the CEU cohort in 500-bp bins across 20 kb centered around the motif CCTCCCTNNCCAC, associated with recombination hotspots. The shaded rectangle denotes two SEM and was obtained from observations excluding the central three bins; the blue curve and 95% confidence band was obtained by loess smoothing with parameter α = 0.2.
