Highly active zinc-finger nucleases by extended modular assembly

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Figure 8.
Figure 8.

Spectrum of sequences targetable using extended MA. (A) An image from the UCSC Genome Browser shows potential extended-MA and CoDA ZFNs sites found within a 60-kb region at the human 9p21 locus (hg18, chr9:22060000-22119999). Each vertical black bar represents a target site. (B) A comparison of the transcript targeting capabilities reported for CoDA and calculated from the data in this study for extended MA.

This Article

  1. Published in Advance December 5, 2012, doi: 10.1101/gr.143693.112 Genome Res. 23: 530-538

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