Different chromatin interfaces of the Drosophila dosage compensation complex revealed by high-shear ChIP-seq

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 6.
Figure 6.

MSL feature enrichment on the transcribed regions correlate well with compensated gene expression. (A) Distribution of MSL-1, MOF, MSL-3, and H4K16ac on X-chromosomal active genes with (red, n = 361) or without (dark blue, n = 752) MSL-1 promoter peaks. Shaded areas above and below the solid lines describe the interquartile range of enrichment. Signals on HAS have been masked for this analysis. (B) Correlation matrix of MSL feature enrichments on promoter or body regions of active genes and functional compensation and distance of the genes from HAS. Pearson correlation coefficients are color-coded as indicated by the scale bar on the right. Signals deriving from HAS have been masked for this analysis.

This Article

  1. Genome Res. 23: 473-485

Preprint Server