TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 6.
Figure 6.

Summary model: Substitution of TRIM28-dependent repressive chromatin by the active marks H3K4me1 and H3K27ac at specific ERV-Up gene pairs parallels activation of gene expression.

This Article

  1. Published in Advance December 10, 2012, doi: 10.1101/gr.147678.112 Genome Res. 23: 452-461

Preprint Server



Current Issue

  1. February 2026, 36 (2)
  1. Current Issue
  1. Alert me to new issues of Genome Research