Figure 5.
The current sequencing depth is not saturated for the detection of dynamic nucleosomes. Counts or functional enrichment Q-values of genes containing dynamic nucleosomes on promoters were plotted as a function of sequencing depth. The sequencing depth is estimated by the read counts multiplied by the nucleosome unit size (200 bp) and divided by the yeast genome size (12 Mb). The biological processes “energy generation by precursor metabolites” (GO:0006091) and “hexose metabolic process” (GO:0019318) were used to estimate the function enrichment of EtOH-YPD and Gal-YPD dynamic nucleosomes, respectively.
