Differentially expressed, variant U1 snRNAs regulate gene expression in human cells

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Figure 3.
Figure 3.

vU1 snRNA genes are up-regulated in hESCs. (A) ChIP analysis of the U1 snRNA and some vU1 snRNA genes in hESCs and HeLa cells with antibodies indicated at the right. (B) qRT-PCR analysis of nascent transcripts from the corresponding U1 snRNA and vU1 snRNA genes in HeLa and hESCs. (Rel. levels) The levels of vU1 snRNA nascent transcripts are expressed relative to U1 snRNA, normalized to 1.0 in each cell type.

This Article

  1. Published in Advance October 15, 2012, doi: 10.1101/gr.142968.112 Genome Res. 23: 281-291

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