Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability

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Figure 2.
Figure 2.

Breakpoints in transcribed and untranscribed regions. Each square represents enrichment (red) or depletion (blue) of breakpoints in transcribed regions defined by maximal distance to transcribed gene. Size represents P-value, and color represents ratio. Only tests that passed 10% FDR are shown. Notice that regions of ∼104 bp were often significantly enriched or depleted. (Right) The average ratio (across samples). The colored bar above specifies the type of cancer for each sample.

This Article

  1. Genome Res. 23: 228-235

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