Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators

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Figure 2.
Figure 2.

Proteins with a relative enrichment of at least fourfold both under mild and stringent washing conditions were investigated for functional protein interactions using the STRING database. Of the 115 significantly enriched proteins, 67 proteins form a functional network containing several established physical complexes: exosome (cyan), polymerase I (dark blue), TFIIIC (light blue), eukaryotic initiations factors (red), replication factor complex (orange), origin recognition complex (violet), SWI-SNF (green), and HDAC-associated complex (yellow).

This Article

  1. Genome Res. 23: 2149-2157

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