
In silico nanodissection. Distribution of cell-type–specific prediction by percentile, estimated using a Gaussian kernel. Genes are ordered on the x-axis from worst (zero percentile) to best (100th percentile). The dotted line shows in silico nanodissection cutoff for the top 136 genes. Nanodissection successfully separates (area under the curve [AUC] 0.83) podocyte-specific genes (green) from genes specific to other renal cell lineages (glomerular endothelial in dark blue, glomerular mesangial in light blue, and tubular in red).











