Estimating inbreeding coefficients from NGS data: Impact on genotype calling and allele frequency estimation

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Figure 1.
Figure 1.

Estimation of inbreeding coefficients. Performance of the EM method to infer Find from called genotypes (left column), Find from genotype likelihoods (center column), and Fsite (right column), for a sample size of 10 (first row) and 30 (second row) individuals and 10,000 variable sites simulated with a 0.5% error rate. Line styles and symbols represent different simulated sequencing coverages. Filled lines represent the inferred value for each simulated scenario (Infer. F), while dotted lines represent its RMSD.

This Article

  1. Genome Res. 23: 1852-1861

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