Figure 4.
The majority of origins reside in non-transcribed chromosomal regions regardless of their firing times, but are significantly associated with transcribed genes in early-replicating regions. (Left) Pie charts of origin distributions across the genome (A), early- (B), mid- (C), and late-replicating (D) regions among the nine annotation categories indicated by the key in E. (Right) Percentages of the genome represented by the nine annotation categories. See Supplemental Tables SIV and SV for numerical distributions and Methods for details of the statistical analysis.
