Hominoid fission of chromosome 14/15 and the role of segmental duplications

Evolutionary history of chromosomes 14 and 15. Ten segments (A–J) are used to track the chromosomal rearrangements and are defined as in Stanyon et al. (2008). The following abbreviations are used: A in red, ancestral centromere; N in red, evolutionary neocentromere; (HSA) Homo sapiens; (PTR) Pan troglodytes; (GGO) Gorilla gorilla; (PPY) Pongo pygmaeus; (MMU) Macaca mulatta; (CJA) Callithrix jacchus. In Figures 1, 2, and 5, chromosomes 14 and 15 are colored according to the color code of the UCSC Genome Browser (dark blue for chromosome 14 and light blue for chromosome 15). The NOR (nucleolus organizer region) bearing short arm is drawn with a horizontal black/white striped box.