
Genome methylation and small RNA. Each point represents a contiguous window of sequence that matches increasing numbers of smRNA reads in size classes of 21 (A), 22 (B), or 24 nt (C) on the x-axis (small RNA count). (Small RNA count) Number of smRNA reads that map to this window and nowhere else with the same number or fewer mismatches. The average methylation level (0–1.00) of each window is plotted on the y-axis (see Methods). Methylation was calculated in CG (green), CHG (blue), and CHH (red) contexts. (ρ) Spearman's rank correlation coefficient (P-value < 0.001).











