Figure 4.
Conservation of DNA sequences encompassing different classes of polyribosome associated alternative mRNA processing events. Local nonlinear smoothing using a generalized additive model shows best-fit sequence conservation (46-way PhyloP) scores of alternative events and flanking sequence. Significant events are depicted as yellow, while “no diff” events are colored blue (shaded 95% confidence interval). (A) Skipped exon events; (B) alternative first exon events; (C) alternative last exon events; and (D) alternative polyadenylation events.
