Alternative splice variants of the LRR region. The schematic depicts alternative splice variants of LRR region coding sequence based on sequencing of RT-PCR products amplified from HeLa cells, G248 lymphoblastoid cell line, human cerebellum, human testis, and mouse testis cDNA. Exons are shown (colored boxes) along with spliced introns (connecting lines), LRR motifs (top), and stop codons (red flags). The splice variants are successively numbered and, except for the ones derived from LRRC37A4, distinguished in a and b according to the presence or absence of exon 8. LRRC37A4 splice variants are indicated (blue). The observed frequency of each product is reported (percentages on left). Human paralogs presenting a specific splice variant are specified (right), with ambiguous assignments indicated in gray.
