Figure 7.
Cell-type–specific sequence models for JUND and YY1 capture different primary motifs. (A) Cell-type–exclusive JUND sites were scored by the GM12878- and K562-specific k-mer SVM models (x- and y-axes, respectively) to identify groups of differentially scored sites. Sites with high K562 and low GM12878 scores (red) and high GM12878 and low K562 scores (blue) were used as input to MEME to produce the different sequence motifs shown with significance P < 10−77. (B) Same as previous panel but using cell-type–exclusive YY1 binding sites with significance P < 10−21.
