Predicting cell-type–specific gene expression from regions of open chromatin

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Figure 6.
Figure 6.

Aggregate plots of DNase-reads around motifs for factors with high regression coefficients. (Red lines) The cell line in which the TF is identified as a regulator. (A) CRX shows a footprint in medulloblastoma but not in the other cell lines shown. (B) REST shows a footprint in other cell lines but not in medulloblastoma, where it is not expressed. (C,D) EGR2 and SPIB show footprints in the GM12878 cell line.

This Article

  1. Genome Res. 22: 1711-1722

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