Long noncoding RNAs are rarely translated in two human cell lines

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 3.
Figure 3.

Manual annotation of non-singleton peptides aligning to GENCODE lncRNA exons: case studies. (A–C) An untranslatable non-singleton peptide encoded downstream from an unprocessed pseudogene. (A) BL2SEQ TBLASTN peptide-to-lncRNA alignment. (B) NCBI ORF Finder view of the translation containing this peptide and upstream stops. (C) UCSC Genome Browser view of the peptide (red box). Direction is positive strand (data not shown). (D–F) An untranslatable non-singleton peptide encoded by a standalone lncRNA exon. (D) BL2SEQ TBLASTN peptide-to-lncRNA alignment. (E) NCBI ORF Finder view of the translation containing this peptide and upstream stops. (F) UCSC Genome Browser view of the peptide (red box) encoded on the negative strand of the genome.

This Article

  1. Genome Res. 22: 1646-1657

Preprint Server