MuSiC: Identifying mutational significance in cancer genomes

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 6.
Figure 6.

Pfam domains affected by OV mutations. (A) A histogram of the most highly mutated domains in the OV data set next to the number of genes affected in each domain. (B) A stacked bar-graph where the value 100% represents the total number of mutations in a particular Pfam domain. Lighter and darker sections of the bars represent which proportions of the total mutations are nonsynonymous and synonymous, respectively.

This Article

  1. Genome Res. 22: 1589-1598

Preprint Server